Kasper joins Sally John, director of translational biology at Biogen, for a conversation about Translational Genetics in Neuroscience, hosted by the Harvard Brain Initiative and the Arlotta Lab.
Frederik Lassen moves to Oxford, UK, to start a PhD program at the Wellcome Centre for Human Genetics. He will continue collaborating with the Lage Lab and we wish him the best of luck in his new scientific endeavors!
Joshua Ching joins the Lage group as part of MIT’s Undergraduate Research Opportunities Program (UROP). He will bring a much appreciated data analysis component to our efforts and will collaborate with senior members in the group. Welcome to the Lage team, Joshua!
Yu-Han and colleagues combined untargeted metabolomics with genetics to identify metabolites that may be causes or effects of obesity. They further grouped these metabolites into pathways to highlight how distinct biological mechanisms may be involved in obesity. Their findings demonstrate the strong potential of using untargeted metabolomics and genetically informed causal inference (Mendelian randomization) to uncover causal biological connections between metabolites and various human diseases, especially as larger datasets with both genotype and metabolite profiling data become available in the future. Congratulations on the great work, Yu-Han!
Kasper joins the Danish national discussion about transparency & openness of the COVID19 models & data in an important effort led by the Danish Prime Minister, Mette Frederiksen, to better communicate COVID19-related information to the public.
Our study co-led by @gretapinta, @flassen_, @yuhanhsu and @mjapkim, ‘Genoppi: an open-source software for robust and standardized integration of proteomic and genetic data’, is now posted as a pre-print on bioRxiv. Genoppi allows the seamless integration of proteomic data with genetic information from a multitude of public or custom gene lists to maximize the interpretation of protein interaction datasets.
Nadine’s work on identification of new biomarkers of Inflammatory Bowel Disease (IBD), under the direction of Ramnik Xavier in collaboration with the Broad Institute, Harvard School of Public Health, the University of North Carolina and Novartis has been published in Nature Microbiology. Fantastic work Nadine!
Find the article here: https://www.nature.com/articles/s41564-019-0655-7
The Brain Interaction Network (BINe) team hosted the February Stanley Center Social and introduced its people to the Stanley Center community.
Taibo has recently been awarded a full MD/PhD scholarship to Johns Hopkins School of Medicine. Taibo started in the Lage Lab in April 2013 and worked on several projects including InWeb, GeNets, BINe, CanComSq. He looks forward to continuing working with the Lage Lab from his new position at Hopkins and we wish him the best of luck!