Kasper Lage
Group Leader, PhD, MBA

Kasper is the Managing Director of the Novo Nordisk Foundation Center for Genomic Mechanisms of Disease, Director of Bioinformatics at the Department of Surgery, Massachusetts General Hospital, Associate Professor at Harvard Medical School, and in the Leadership Group of the Stanley Center for Psychiatric Research at Broad Institute.

Travis Botts
Senior Research Associate

Travis obtained his undergraduate degree in Biochemistry from Curry College. His undergraduate thesis was the observation of the knockdown of genes in mammalian cells and the resulting changes in expression level. After working at EMD Serono, Takeda and Biogen, he joined the Lage Lab at the Broad in 2022 as a Senior Research Associate in support of research of the genetic causes of autism spectrum disorders and schizophrenia.

Joshua Ching
UROP Student

Joshua studied Bioengineering at the University of Hong Kong before transferring to Northeastern University, where he is currently majoring in Computer Science and Cognitive Psychology. He has also studied Computer Science and Neuroscience during his exchange year at Massachusetts Institute of Technology.

Yu-Han Hsu
Computational Scientist

Yu-Han obtained her PhD in Biomedical Informatics from Harvard University. Her doctoral research with Dr. Joel Hirschhorn combined metabolomic and genetic data to study obesity. In the Lage Lab, she develops computational methods that integrate cell-type-specific PPI networks with multi-omic data types to study psychiatric and other complex disorders.

Frederik Heymann Lassen
Visiting Graduate Student

Frederik obtained his undergraduate degree in Bioengineering at the Technical University of Denmark and has studied bioinformatics at both the Australian National University and Massachusetts Institute of Technology. He is currently a graduate student at the Wellcome Centre for Human Genetics at the University of Oxford.

Makayla Martorana
Research Associate

Makayla received her undergraduate degree in Biochemistry from Simmons University. Her undergraduate thesis focused on construction of a synthetic mycobacterium phage genome using transformation-associated recombination (TAR) cloning in Saccharomyces Cerevisiae. She then received a Master of Science degree from Boston University Chobanian & Avedisian School of Medicine. Her master’s thesis focused on investigating the impact of IL-17A signaling in osteoclasts and osteoblasts on bone loss in spondyloarthritis and estrogen deficiency. She joined the Lage Lab in 2023 as a Research Associate.

Daya Mena
Research Associate

Daya obtained her BA in Biomedical and Biomathematical Sciences from Hampshire College in 2019. Her undergraduate thesis was on using mathematical modeling to predict the impact of gene editing on HIV therapy. In 2020, Daya joined the Pan Lab in the Stanley Center Therapeutics Group before joining the Lage Lab.

Petra Páleníková
Postdoctoral Associate

Petra obtained her PhD in Medical Sciences from the MRC Mitochondrial Biology Unit at the University of Cambridge. Her doctoral research focused on the study of mitochondrial translation and biogenesis of the mitochondrial ribosome. She joined the Lage Lab as a Postdoctoral Associate in May 2022 to apply computational methods to the study of protein interaction networks in neuropsychiatric disorders and gene regulation in health and disease.

Greta Pintacuda
Research Scientist

Greta earned her D.Phil. in molecular and cell biology and biochemistry from the University of Oxford. She completed postdoctoral training in the labs of Kevin Eggan and Kasper Lage at the Broad Institute and at Harvard University. She contributed to conceiving experimental plans aimed at combining human genetics, human neural cell models, and biochemistry, to investigate molecular mechanisms affected in neuropsychiatric and neurodevelopmental disorders, including autism spectrum disorders, schizophrenia, and post-traumatic stress disorders.

Danzel Rebelo
Research Associate

Danzel received his Bachelor of Science in bioengineering with a focus on cell and tissue engineering from Northeastern University in 2023. His undergraduate thesis was on developing a testing apparatus through which the efficacy of a device designed to prevent transmission and inhalation of airborne pathogens and pollutants using miniaturized laminar flow could be examined. He joined the Lage Lab in 2023 as a Research Associate.

Paulina Strzelecka
Research Scientist

Paulina obtained her PhD in Biochemistry from University of Gdansk, Poland. She then moved to University of Cambridge/Wellcome Sanger Institute, UK to start a postdoctoral position. Her research there focused on application of single-cell techniques to study hematopoietic cell differentiation and immune cell heterogeneity. In 2019, Paulina was awarded a Humboldt Fellowship for Postdoctoral Researchers and she moved to Germany where she applied single-cell multiomics techniques to better understand consequences of disease-associated cell states. She joined the Lage Lab in November 2023 as a Research Scientist.  

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