We’re happy to announce that Kasper Lage joined the National Institutes of Health Accelerating Medicines Partnership in type 2 diabetes to work on cell-type-specific protein networks involved in type 2 diabetes together with Jose Florez, Chad Cowan, Mark McCarthy, Anna Gloyn and Rob Sladek.

For more information about the NIH Accelerating Medicines Partnership: click here.

For more information about Anna Gloyn: click here.

For more information about Chad Cowan: click here.

For more information about Mark McCarthy: click here.

For more information about Jose Florez: click here.

For more information about Rob Sladek: click here.

We’re delighted to announce that the Lage Lab has been awarded a three year grant from the Lundbeck Foundation to study the protein networks perturbed by genetics in psychiatric diseases. This project will enable us to strengthen our current experimental work in the Stanley Center for Psychiatric Research at the Broad Institute and is a collaboration with the Danish iPSYCH consortium. The grant will furthermore support training of Danish postdocs in the Lage Lab and at the Broad Institute.

For more information about the Stanley Center: See here.

For more information about the iPSYCH consortium: See here.

For more information about the Lundbeck Foundation: See here.

Today the Lage Lab published an article describing a quality controlled and scored human protein-protein interaction network to help functionally interpreting genomic data. Congratulations to Taibo Li, Heiko Horn and Kasper Lage.

Link to Nature Methods webpage: article.

Link to Broad Institute Snapshot on the article: Broad Institute Snapshot.

Link to press release from MGH: MGH press release.

For more information see here: InWeb_IM.

For more information see here: Broad Institute highlights from ASHG 2016 in Vancouver.

For more information click here.

Time: Wednesday, October 19, 11:00 AM–1:00 PM

Title: Augmenting and Interpreting Genomic Data Using Tissue- and Cell-type-specific Networks

Loctaion: Room 221, West Building, Convention Centre

11:00 AM   Cell-type-specific protein interaction networks perturbed by genetics in psychiatric diseases. K. Lage. Broad Institute / Harvard U.

11:30 AM   Transcriptome-wide networks for understanding diverse categories of genetic variation. A. Battle. Johns Hopkins University.

12:00 PM   Tissue-specific networks for integrative disease gene identification. O. Troyanskaya. Princeton University.

12:30 PM   Building multi-omic networks for type 2 diabetes and related phenotypes. M. McCarthy. Oxford University.

We are happy to welcome Anna Sappington (MIT undergraduate studying Computer Science and Molecular Biology) and Justin Lim (MIT undergraduate studying Mathematics and Computer Science) to the lab.

Anna and Justin will be working on Broadnex10 projects to map cellular network perturbed by genetics in early onset myocardial infraction and the Cancer Complex Compendium. For more information about these projects click here.

On June 23rd and 24th Kasper was invited for a two day visit to the Jackson Laboratory for Genomic Medicine in Conneticut where he presented his labs work.

During this time he met with the Institute’s Leadership (Edison Liu and Charles Lee) as well as with the impressive young faculty of this newly created research site.

Edyta Malolepsza, April Kim and Kasper Lage attended the annual meeting of the “The Lundbeck Foundation Initiative for Integrative Psychiatric Research” – iPSYCH – consortium June 1st to 4th  where Kasper was invited to give a Keynote Address titled ‘Human Brain Networks Perturbed by Genetics and Targeted by Therapeutics in Psychiatric Disorders.

For more information about the iPSYCH meeting click here.

From the iPSYCH website (http://ipsych.au.dk/):  “The Lundbeck Foundation Initiative for Integrative Psychiatric Research” – iPSYCH project will study five specific mental disorders; autism, Attention Deficit Hyperactive Disorder (ADHD), schizophrenia, bipolar disorder and depression. All disorders are associated with major human and societal costs all over the world. The project will study these disorders from many different angles, ranging from genes and cells to population studies, from fetus to adult, from cause to symptoms of the disorder, and this knowledge will be combined in new ways across scientific fields.

The main goals are to identify the causes of these disorders by studying the genetic and environmental factors. The perspective is to offer better and more personalized treatment, providing a better life for each individual patient – and perhaps even ways to prevent the development of the disorder in some cases.

Kasper presented the labs work on this two day meeting on the Biogen Campus in Cambridge US.

For more information see here:

Kasper presented the labs work on neurological diseases and participated in brainstorming sessions on new ways to tackle neurological diseases this two-day meeting at the Google Headquarters on Kendall Square in Cambridge (USA).

For more information about the event see here: ms-innovation-workshop-agenda-details-v2