Our study co-led by @gretapinta, @flassen_, @yuhanhsu and @mjapkim, ‘Genoppi: an open-source software for robust and standardized integration of proteomic and genetic data’, is now posted as a pre-print on bioRxiv. Genoppi allows the seamless integration of proteomic data with genetic information from a multitude of public or custom gene lists to maximize the interpretation of protein interaction datasets.

The cancer network algorithm paper titled “Prediction of cancer driver genes through network-based moment propagation of mutation scores” has been accepted for presentation at ISMB 2020 and for inclusion in the conference proceedings. This work is in collaboration with Karsten Borgwardt and led by Heiko Horn and Anja Gumpinger.

Kasper presented the Stanley Center Brain Interaction Network project to the Open Targets Community. Great job Kasper!

Kasper recently interviewed with Vivien Marx on her Nature Methods Technology Feature titled ‘Bench pressing with genomics benchmarkers,’ which highlights the importance of benchmarking for genomics softwares. The insightful article can be found here: https://www.nature.com/articles/s41592-020-0768-1?proof=trueatural-gas-cut-pollution-saved-lives%2F

Congratulations to Frederik Heymann Lassen on being accepted to the PhD program in Genomics Medicine and Statistics at Oxford University led by Julian Knight and John Todd!

Nadine’s work on identification of new biomarkers of Inflammatory Bowel Disease (IBD), under the direction of Ramnik Xavier in collaboration with the Broad Institute, Harvard School of Public Health, the University of North Carolina and Novartis has been published in Nature Microbiology. Fantastic work Nadine!

Find the digest here: https://naturemicrobiologycommunity.nature.com/users/346662-nadine-fornelos/posts/58611-gut-bugs-and-metabolites.

Find the article here: https://www.nature.com/articles/s41564-019-0655-7

The Brain Interaction Network (BINe) team hosted the February Stanley Center Social and introduced its people to the Stanley Center community.

Kasper hosted the Stanley Center Program Meeting where he gave a talk titled “Functional interpretation of genetic data in psychiatric diseases using human neuronal protein-protein interaction networks.” In addition, Yu-Han Hsu and Greta Pintacuda, postdocs in the Lage Lab and Eggan Lab, presented their work titled “Combining proteomics with human genetics to study neuropsychiatric disease.” Great job everyone!

Poster led by Greta Pintacuda from Kevin Eggan’s lab on our joint Stanley Center at the Broad Institute project to map protein networks of psychiatric risk genes in human neurons won both the popular poster award and judge-based vote at The 2019 Broad Retreat. Only 12 awards were given to 260 featured posters. Congratulations BINe team!

Kasper gave a plenary talk at World Congress of Psychiatric Genetics 2019 where he discussed the functional interpretation of genetic data in psychiatric diseases and the insights from tissue specific protein-protein interaction networks for schizophrenia.